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About

Novo Aesthetics is a day spa, located at 4900 E 57th St Ste B, Sioux Falls, SD 57108. They can be contacted via phone at (605) 359-3877 or email at [email protected], visit their website www.novo-spa.com, Facebook, or Instagram profile for more detailed information.

Novo Aesthetics is a trusted medical spa and weight loss clinic serving Sioux Falls, SD and surrounding communities across South Dakota, Minnesota, and Iowa. We offer personalized med spa treatments and advanced weight loss programs designed to help patients look and feel their best through evidence-based, minimally invasive care. Our licensed medical professionals combine aesthetic expertise with individualized treatment planning, delivering services that address everything from skin rejuvenation and facial contouring to medically supervised weight management. Whether patients are seeking to restore confidence in their appearance or achieve lasting weight loss results, Novo Aesthetics provides the clinical experience and compassionate care to make it happen.

Tags : #MedicalSpa

Location :
4900 E 57th St Ste B, Sioux Falls, SD 57108
Added by Novo Aesthetics, at 02 June 2026

Opening Hours

  • Monday 9:00 AM - 5:00 PM
  • Tuesday 9:00 AM - 5:00 PM
  • Wednesday 9:00 AM - 5:00 PM
  • Thursday 9:00 AM - 5:00 PM
  • Friday 9:00 AM - 5:00 PM
  • Saturday Closed
  • Sunday Closed

Products and Services

  • Weight Loss Service
  • Skin Care Clinic
  • Botox Clinic
  • Facial Spa
  • Medical Clinic or Nurse Practitioner

Anti-Wrinkle Injections (Xeomin & Dysport):

Novo Aesthetics offers professional anti-wrinkle injections using Xeomin and Dysport to smooth fine lines, frown lines, and crow's feet caused by repeated facial muscle movement. Our medical team administers these neuromodulator treatments with precision, targeting the specific muscles responsible for dynamic wrinkles and delivering a natural, refreshed appearance that lasts two to four months. With sessions typically taking just 20 minutes and requiring no downtime, Novo Aesthetics makes it easy for patients across Sioux Falls and beyond to maintain younger-looking skin without disrupting their daily routine.

Weight Loss Program (Semaglutide & Tirzepatide):

Novo Aesthetics provides medically supervised weight loss programs using GLP-1 medications like semaglutide and tirzepatide, offering patients in Sioux Falls and across the region a clinically proven path to sustainable weight reduction. Our experienced medical professionals conduct personalized consultations to develop customized treatment plans that address metabolism, appetite regulation, and overall health — not just the number on the scale. With remote consults available and multiple clinic locations throughout South Dakota, Minnesota, and Iowa, Novo Aesthetics makes advanced medical weight loss more accessible than ever for patients ready to take control of their health.

Microneedling with PRP:

Novo Aesthetics offers microneedling with platelet-rich plasma (PRP) therapy, a powerful skin rejuvenation treatment that harnesses the body's own healing response to stimulate collagen and elastin production. Our medical spa team uses precision microneedling techniques combined with the patient's own PRP to visibly improve skin texture, tone, and brightness while reducing the appearance of wrinkles, fine lines, and acne scars. We recommend a series of three treatments over three months for optimal results, and Novo Aesthetics guides each patient through a personalized care plan that supports long-term skin health and lasting aesthetic improvement.

Frequently Asked Questions (FAQ)

  • What kind of weight loss treatments does Novo Aesthetics offer??
    Novo Aesthetics offers medically supervised weight loss programs using GLP-1 medications including semaglutide and tirzepatide. The clinic serves patients in Sioux Falls, SD, Watertown, SD, Luverne, MN, Sioux Center, IA, Primghar, IA, and Orange City, IA, with remote consultations also available. Novo Aesthetics provides personalized treatment plans developed by licensed medical professionals to support sustainable weight loss through appetite regulation and metabolic improvement.
  • Where can I get Botox or anti-wrinkle injections near Sioux Falls, SD??
    Novo Aesthetics provides anti-wrinkle injections using Xeomin and Dysport at their Sioux Falls, SD location at 4900 E 57th St Suite B. The medical spa serves patients from Sioux Falls and surrounding communities across South Dakota, Minnesota, and Iowa. Novo Aesthetics administers neuromodulator treatments in approximately 20-minute sessions with no downtime, targeting fine lines, frown lines, and crow's feet for results lasting two to four months.
  • Does Novo Aesthetics offer dermal fillers for lips and cheeks??
    Novo Aesthetics offers dermal filler treatments designed to restore lost volume, smooth lines, and enhance facial contours in areas such as the lips and cheeks. The med spa uses gel-based injectable fillers that deliver immediate results lasting six to twelve months or more, with sessions completed in approximately 45 minutes. Novo Aesthetics serves patients across Sioux Falls, SD, Watertown, SD, and multiple locations throughout Minnesota and Iowa seeking natural-looking facial rejuvenation.
  • What is a VI Peel and is it good for acne scars or dark spots??
    Novo Aesthetics uses the VI Peel system to treat a range of skin concerns including acne, acne scars, sunspots, hyperpigmentation, melasma, and uneven skin tone. The VI Peel is suitable for all skin types, including sensitive skin and darker skin tones, and works by exfoliating the skin while delivering vitamins and minerals to support skin health. Novo Aesthetics offers VI chemical peel treatments at locations in Sioux Falls, SD and across their network of clinics in South Dakota, Minnesota, and Iowa.
  • Is microneedling with PRP worth it for skin texture and fine lines??
    Novo Aesthetics provides microneedling with PRP therapy, a treatment that combines precision microneedling with the patient's own platelet-rich plasma to stimulate collagen and elastin production. The treatment improves skin texture, tone, and brightness while reducing the appearance of fine lines, wrinkles, and scarring, with optimal results achieved through a series of three sessions over three months. Novo Aesthetics recommends this treatment to patients throughout Sioux Falls, SD and surrounding service areas in South Dakota, Minnesota, and Iowa who are looking for clinically effective, non-surgical skin rejuvenation.

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